Compare-N-Save 41% Glyphosate Grass & Weed Killer Concentrate Review (2026)
By The DIYPicks Team · Updated July 2026
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- Large areas
- Perennial weeds
- Systemic kill
- Fence lines
A conventional, budget systemic herbicide for clearing large or perennial weed problems root-and-all — powerful but non-selective, so use PPE, follow the label, and consider lower-toxicity options for small jobs.
Pros
- Systemic action kills weeds down to the root, including tough perennials that vinegar only burns back
- Very economical — a small concentrate bottle makes many gallons of spray for large areas
- Rainproof within about 2 hours and effective on a broad range of weeds and grasses
Cons
- Non-selective — will kill any green plant it contacts, including lawn grass and garden plants
- Synthetic herbicide with label PPE and re-entry requirements; glyphosate is subject to ongoing health debate and some local restrictions — read the label and check local rules
- Can move within/through plants and requires care near desirable roots, water, and pollinator-visited blooms
Specifications
| Active | Glyphosate 41% (isopropylamine salt) |
|---|---|
| Organic | No — conventional synthetic herbicide |
| Targets | Broadleaf & grassy weeds, systemic (kills to the root) |
| Use on edibles | Non-selective; keep off crops and desirable plants — see label pre-plant intervals |
| Safety | Wear gloves/eye protection; keep off pollinator plants; keep pets/kids off until dry. Follow label & local rules |